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Literature summary extracted from

  • Rubin, P.M.; Zahler, W.L.; Randall, D.D.
    Plant pyruvate dehydrogenase complex: analysis of the kinetic properties and metabolite regulation (1978), Arch. Biochem. Biophys., 188, 70-77.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.2.1.104 beta-Hydroxypyruvate competitive vs. pyruvate Brassica oleracea
1.2.1.104 glyoxylate noncompetitive vs. pyruvate Brassica oleracea

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.2.1.104 mitochondrion
-
 Brassica oleracea 5739
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.2.1.104 Ca2+ can replace Mg2+ Brassica oleracea
1.2.1.104 Mg2+
-
 Brassica oleracea
1.2.1.104 Mn2+ can replace Mg2+ Brassica oleracea

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.104 Brassica oleracea
-
 var. italica, cauliflower, broccoli
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.2.1.104 floret
-
 Brassica oleracea
-

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.104 thiamine diphosphate
-
 Brassica oleracea

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.2.1.104 0.11
-
 Hydroxypyruvate
-
 Brassica oleracea
1.2.1.104 3.27
-
 glyoxylate
-
 Brassica oleracea