Literature summary extracted from

Danson, M.J.; Hale, G.; Johnson, P.; Perham, R.N.
Molecular weight and symmetry of the pyruvate dehydrogenase multienzyme complex of Escherichia coli (1979), J. Mol. Biol., 129, 603-617.

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
1.2.1.104	100000	-	sucrose density gradient centrifugation	Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2.3.1.12	dihydrolipoamide + acetyl-CoA	Escherichia coli	-	S-acetyldihydrolipoamide + CoA	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.2.1.104	Escherichia coli	-	-	-
2.3.1.12	Escherichia coli	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
2.3.1.12	pyruvate dehydrogenase complex, stoichiometry E1:E2:E3 is 1.56:1:0.89	Escherichia coli

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.3.1.12	dihydrolipoamide + acetyl-CoA	-	Escherichia coli	S-acetyldihydrolipoamide + CoA	-	?

Subunits

EC Number	Subunits	Comment	Organism
2.3.1.12	polymer	22 or 24 subunits	Escherichia coli

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Release 2023.1 (January 2023)