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Literature summary extracted from

  • Phelps, A.; Lindsay, J.G.
    Mammalian pyruvate dehydrogenase complex binds tightly to the mitochondrial inner membrane (1986), Biochem. Soc. Trans., 14, 893.
No PubMed abstract available

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.2.1.104 mitochondrion subunit E1, EC 1.2.4.1, of whole enzyme complex has lower affinity to membrane than E2, EC 1.8.1.4 Bos taurus 5739
-
2.3.1.12 mitochondrial inner membrane pyruvate dehydrogenase complex bound to inner mitochondrial membrane Bos taurus 5743
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.12 dihydrolipoamide + acetyl-CoA Bos taurus
-
 S-acetyldihydrolipoamide + CoA
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.104 Bos taurus
-
-
-
2.3.1.12 Bos taurus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.2.1.104 heart
-
 Bos taurus
-
2.3.1.12 heart
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.12 dihydrolipoamide + acetyl-CoA
-
 Bos taurus S-acetyldihydrolipoamide + CoA
-
 ?