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Literature summary extracted from

  • MacGibbon, A.K.H.; Motion, R.L.
    Purification and properties of sheep-liver aldehyde dehydrogenases (1979), Eur. J. Biochem., 96, 585-595.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.2.1.3 5,5'-dithio-bis-(2-nitrobenzoic acid)
-
 Ovis aries

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.2.1.3 cytoplasm
-
 Ovis aries 5737
-
1.2.1.3 mitochondrion
-
 Ovis aries 5739
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.2.1.3 additional information enzyme does not contain significant amounts of metal ion Ovis aries

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.2.1.3 53000
-
 4 * 53000, SDS-PAGE Ovis aries
1.2.1.3 205000
-
 mitochondrial enzyme, gel filtration Ovis aries
1.2.1.3 212000
-
 cytoplasmic enzyme, gel filtration Ovis aries

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.3 Ovis aries
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.2.1.3 cytoplasmic enzyme Ovis aries

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.2.1.3 liver
-
 Ovis aries
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.2.1.3 0.38
-
-
 Ovis aries

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.3 acetaldehyde + NAD+ + H2O
-
 Ovis aries acetate + NADH + H+
-
 ?
1.2.1.3 benzaldehyde + NAD+ + H2O
-
 Ovis aries benzoate + NADH + H+
-
 ?
1.2.1.3 butanal + NAD+ + H2O
-
 Ovis aries butyrate + NADH + H+
-
 ?
1.2.1.3 D-glucose + NAD+ + H2O
-
 Ovis aries D-glucuronic acid + NADH
-
 ?
1.2.1.3 formaldehyde + NAD+ + H2O
-
 Ovis aries formate + NADH
-
 ?
1.2.1.3 m-nitrobenzaldehyde + NAD+ + H2O
-
 Ovis aries m-nitrobenzoate + NADH
-
 ?
1.2.1.3 p-methoxybenzaldehyde + NAD+ + H2O
-
 Ovis aries p-methoxybenzoate + NADH + H+
-
 ?
1.2.1.3 p-nitrobenzaldehyde + NAD+ + H2O
-
 Ovis aries p-nitrobenzoate + NADH
-
 ?
1.2.1.3 propanal + NAD+ + H2O
-
 Ovis aries propionate + NADH
-
 ?
1.2.1.3 pyridine-3-aldehyde adenine dinucleotide + NAD+ + H2O
-
 Ovis aries pyridine-3-carboxylate adenine dinucleotide + NADH
-
 ?

Subunits

EC Number Subunits Comment Organism
1.2.1.3 tetramer 4 * 53000, SDS-PAGE Ovis aries

pH Range

EC Number pH Minimum pH Maximum Comment Organism
1.2.1.3 7.6
-
-
 Ovis aries

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.3 NAD+
-
 Ovis aries