Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Siew, C.; Deitrich, R.A.
    Localization and characteristics of rat liver mitochondrial aldehyde dehydrogenases (1976), Arch. Biochem. Biophys., 176, 638-649.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.2.1.3 0.0007
-
 pentanal
-
 Rattus norvegicus
1.2.1.3 0.0015
-
 acetaldehyde
-
 Rattus norvegicus
1.2.1.3 0.003
-
 NAD+ reaction with propanal Rattus norvegicus
1.2.1.3 0.0056
-
 Heptanal
-
 Rattus norvegicus
1.2.1.3 0.013
-
 Pyruvic aldehyde
-
 Rattus norvegicus
1.2.1.3 0.014
-
 4-cyanobenzaldehyde
-
 Rattus norvegicus
1.2.1.3 0.022
-
 3-acetylpyridine-NAD+
-
 Rattus norvegicus
1.2.1.3 0.024
-
 p-Carboxybenzaldehyde
-
 Rattus norvegicus
1.2.1.3 0.027
-
 phenylacetaldehyde
-
 Rattus norvegicus
1.2.1.3 0.031
-
 formaldehyde
-
 Rattus norvegicus
1.2.1.3 0.031
-
 propanal
-
 Rattus norvegicus
1.2.1.3 0.032
-
 crotonaldehyde
-
 Rattus norvegicus
1.2.1.3 0.036
-
 Isobutanal
-
 Rattus norvegicus
1.2.1.3 0.043
-
 Glyoxal
-
 Rattus norvegicus
1.2.1.3 0.043
-
 Monochloroacetaldehyde
-
 Rattus norvegicus
1.2.1.3 0.045
-
 glycolaldehyde
-
 Rattus norvegicus
1.2.1.3 0.326
-
 deamino-NAD+
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.2.1.3 mitochondrion enzyme I is localized in the matrix Rattus norvegicus 5739
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.2.1.3 320000
-
 enzyme I, gel filtration Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.3 Rattus norvegicus
-
 enzyme I
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.2.1.3
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.2.1.3 liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.2.1.3 0.232
-
 enzyme I Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.3 4-cyanobenzaldehyde + NAD+ + H2O
-
 Rattus norvegicus 4-cyanobenzoate + NADH
-
 ?
1.2.1.3 acetaldehyde + NAD+ + H2O
-
 Rattus norvegicus acetate + NADH + H+
-
 ?
1.2.1.3 butanal + NAD+ + H2O
-
 Rattus norvegicus butyrate + NADH + H+
-
 ?
1.2.1.3 crotonaldehyde + NAD+ + H2O
-
 Rattus norvegicus crotonate + NADH
-
 ?
1.2.1.3 formaldehyde + NAD+ + H2O
-
 Rattus norvegicus formate + NADH
-
 ?
1.2.1.3 glycolaldehyde + NAD+ + H2O
-
 Rattus norvegicus glycolate + NADH
-
 ?
1.2.1.3 glyoxal + NAD+ + H2O
-
 Rattus norvegicus oxalate + NADH
-
 ?
1.2.1.3 heptanal + NAD+ + H2O
-
 Rattus norvegicus heptanoate + NADH
-
 ?
1.2.1.3 isobutanal + NAD+ + H2O
-
 Rattus norvegicus isobutyrate + NADH
-
 ?
1.2.1.3 monochloroacetaldehyde + NAD+ + H2O
-
 Rattus norvegicus monochloroacetate + NADH
-
 ?
1.2.1.3 p-carboxybenzaldehyde + NAD+ + H2O
-
 Rattus norvegicus p-carboxybenzoate + NADH
-
 ?
1.2.1.3 pentanal + NAD+ + H2O
-
 Rattus norvegicus pentanoate + NADH
-
 ?
1.2.1.3 phenylacetaldehyde + NAD+ + H2O
-
 Rattus norvegicus phenylacetate + NADH + H+
-
 ?
1.2.1.3 propanal + 3-acetylpyridine-NAD+ + H2O
-
 Rattus norvegicus propionate + 3-acetylpyridine-NADH
-
 ?
1.2.1.3 propanal + deamino-NAD+ + H2O
-
 Rattus norvegicus propionate + deamino-NADH
-
 ?
1.2.1.3 propanal + NAD+ + H2O
-
 Rattus norvegicus propionate + NADH
-
 ?
1.2.1.3 pyruvic aldehyde + NAD+ + H2O
-
 Rattus norvegicus pyruvate + NADH
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.3 additional information no activity with NADP+ Rattus norvegicus
1.2.1.3 NAD+
-
 Rattus norvegicus