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Literature summary extracted from

  • Bocanera, L.V.; Martinetto, H.; Flawia, M.M.; Pisarev, M.A.
    Partial characterization of guanylyl cyclase activity in calf thyroid (1999), Endocr. Res., 25, 215-228.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
4.6.1.2 atrial natriuretic peptide activation of the particulate form Bos taurus
4.6.1.2 sodium nitroprusside activation of the soluble form Bos taurus
4.6.1.2 Triton X-100 activation Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.6.1.2 0.037
-
 GTP soluble form Bos taurus
4.6.1.2 0.752
-
 GTP particulate form Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.6.1.2 particle-bound
-
 Bos taurus
-
-
4.6.1.2 soluble
-
 Bos taurus
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
4.6.1.2 Ca2+ activation of soluble enzyme Bos taurus
4.6.1.2 Mn2+
-
 Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
4.6.1.2 Bos taurus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.6.1.2 thyroid gland
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.6.1.2 GTP GTP in form of MnGTP2- Bos taurus 3',5'-cyclic GMP + diphosphate
-
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