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Literature summary extracted from

  • Chiarugi, A.; Cozzi, A.; Massacesik L.; Moroni, F.
    Kynurenine 3-momo-oxygenase activity and neurotoxic kynurenine metabolites increase in the spinal cord of rats with experimental allergic encephalomyelitis (2001), Neuroscience, 102, 687-695.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.14.13.9 cytoplasmic vesicle
-
 Rattus norvegicus 31410
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.13.9 L-kynurenine + NADPH + O2 Rattus norvegicus increased activity in the spinal cord with experimental allergic encephalopathy ? + NADP+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.13.9 Rattus norvegicus
-
 female wistar rat
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.13.9 brain neurons and astrocytes Rattus norvegicus
-
1.14.13.9 spinal cord
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.14.13.9 additional information
-
 specific activity in organs of rats with experimental allergic encephalopathy Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.13.9 L-kynurenine + NADPH + O2
-
 Rattus norvegicus 3-hydroxy-L-kynurenine + NADP+ + H2O
-
 ?
1.14.13.9 L-kynurenine + NADPH + O2 increased activity in the spinal cord with experimental allergic encephalopathy Rattus norvegicus ? + NADP+
-
 ?