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Literature summary extracted from

  • Okamoto, H.; Hayaishi, O.
    Flavin adenine dinucleotide requirement for kynurenine hydroxylase of rat liver mitochondria (1967), Biochem. Biophys. Res. Commun., 29, 394-399.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.14.13.9 0.0003
-
 FAD
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.14.13.9 mitochondrial outer membrane
-
 Rattus norvegicus 5741
-
1.14.13.9 mitochondrion
-
 Rattus norvegicus 5739
-

Organism

EC Number Organism UniProt Comment Textmining
1.14.13.9 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.13.9 liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.14.13.9 additional information
-
 20000000 cpm per micromole Rattus norvegicus
1.14.13.9 47
-
 native Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.13.9 L-kynurenine + NADPH + O2
-
 Rattus norvegicus 3-hydroxy-L-kynurenine + NADP+ + H2O
-
 ?

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
1.14.13.9 100
-
 no enzymatic activity after boiling Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.13.9 FAD flavoprotein Rattus norvegicus
1.14.13.9 NADPH
-
 Rattus norvegicus