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Literature summary extracted from

  • White, A.A.; Zenser, T.V.
    Preparation and characterization of guanylate cyclase from bovine lung (1974), Methods Enzymol., 38C, 192-195.
    View publication on PubMed

General Stability

EC Number General Stability Organism
4.6.1.2 glycerol stabilizes Bos taurus
4.6.1.2 sucrose stabilizes Bos taurus

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.6.1.2 Cd2+
-
 Bos taurus
4.6.1.2 Hg2+
-
 Bos taurus
4.6.1.2 oxaloacetate
-
 Bos taurus
4.6.1.2 phosphoenolpyruvate
-
 Bos taurus
4.6.1.2 Zn2+
-
 Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.6.1.2 0.02 0.1 GTP
-
 Bos taurus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
4.6.1.2 Ca2+ activation of soluble enzyme Bos taurus
4.6.1.2 Mg2+
-
 Bos taurus
4.6.1.2 Mn2+
-
 Bos taurus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.6.1.2 300000
-
 gel filtration Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
4.6.1.2 Bos taurus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.6.1.2
-
 Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.6.1.2 lung
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.6.1.2 GTP
-
 Bos taurus 3',5'-cyclic GMP + diphosphate
-
 ir

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.6.1.2 7.4 7.6
-
 Bos taurus