Literature summary extracted from

Dessauer, C.W.; Gilman, A.G.
The catalytic mechanism of mammalian adenylyl cyclase. Equilibrium binding and kinetic analysis of P-site inhibition (1997), J. Biol. Chem., 272, 27787-27795.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
4.6.1.1	forskolin	activation	Mammalia

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
4.6.1.1	-	Mammalia

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
4.6.1.1	2'-deoxyadenosine	-	Mammalia
4.6.1.1	alpha,beta-methylene adenosine 5'-triphosphate	in presence of diphosphate	Mammalia
4.6.1.1	cAMP	in presence of diphosphate	Mammalia
4.6.1.1	diphosphate	-	Mammalia

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.6.1.1	Mammalia	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4.6.1.1	ATP	-	Mammalia	3',5'-cAMP + diphosphate	-	r

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Release 2023.1 (January 2023)