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Literature summary extracted from

  • Carr, S.F.; Papp, E.; Wu, J.C.; Natsumeda, Y.
    Characterization of human type I and type II IMP dehydrogenases (1993), J. Biol. Chem., 36, 27286-27290.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.205 Mycophenolic acid type II enzyme is 4.8fold more sensitive than type I Homo sapiens
1.1.1.205 NADH
-
 Homo sapiens
1.1.1.205 xanthosine 5'-phosphate
-
 Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.205 additional information
-
 additional information
-
 Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.1.1.205 56000
-
 4 * 56000 density gradient centrifugation Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.205 Homo sapiens
-
 type II
-

Subunits

EC Number Subunits Comment Organism
1.1.1.205 tetramer 4 * 56000 density gradient centrifugation Homo sapiens

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.1.1.205 additional information
-
 additional information various substrates Homo sapiens
1.1.1.205 0.0217
-
 NAD+ type II enzyme Homo sapiens
1.1.1.205 0.025
-
 NAD+ type I enzyme Homo sapiens

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.1.1.205 additional information
-
 additional information
-
 Homo sapiens