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Literature summary extracted from

  • Xiang,B.; Taylor, J.C.; Markham, G.D.
    Monovalent cation activation and kinetic mechanism of inosine 5'-monophosphate dehydrogenase (1996), J. Biol. Chem., 271, 1435-1440.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.205 type II Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.205 NADH non competitive with respect to K+, IMP and NAD Homo sapiens
1.1.1.205 xanthosine 5'-phosphate competitive with respect to IMP Homo sapiens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.1.1.205 K+ requirement, maximal activity at 20 mM Homo sapiens
1.1.1.205 Tl+ activation, maximal activity at 5 mM Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.205 Homo sapiens
-
 type II
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.205 homogeneity Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.205 lymphoblast
-
 Homo sapiens
-
1.1.1.205 lymphocyte
-
 Homo sapiens
-

Storage Stability

EC Number Storage Stability Organism
1.1.1.205 -80°C, can be indefinitely stored without loss of activity Homo sapiens
1.1.1.205 4°C, no loss of activity after 3 days Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.205 7.7
-
 at 37°C Homo sapiens