EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.205 | 5'-thio-IMP | competitive inhibitor | Klebsiella aerogenes | |
1.1.1.205 | 6-thioinosine 5'-phosphate | in absence of glutathione | Klebsiella aerogenes | |
1.1.1.205 | xanthosine 5'-phosphate | product inhibitor | Klebsiella aerogenes |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.1.1.205 | 0.013 | - |
5'-mercapto-5'-deoxyinosine 5'-S-phosphate | - |
Klebsiella aerogenes | |
1.1.1.205 | 0.038 | - |
5'-Amino-5'-deoxyinosine 5'-N-phosphate | - |
Klebsiella aerogenes | |
1.1.1.205 | 0.21 | - |
Inosine 5'-phosphorothioate | - |
Klebsiella aerogenes |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.1.1.205 | Klebsiella aerogenes | - |
- |
- |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
1.1.1.205 | IMP + NAD+ + H2O = XMP + NADH + H+ | enzyme acts on the hydroxyl group of the hydrated derivative of the substrate, ordered bi-bi mechanism | Klebsiella aerogenes |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.205 | 5'-amino-5'-deoxyinosine 5'-N-phosphate + NAD+ + H2O | - |
Klebsiella aerogenes | 5'-amino-5'-deoxyxanthosine 5'-N-phosphate + NADH | - |
? | |
1.1.1.205 | 5'-mercapto-5'-deoxyinosine 5'-S-phosphate + NAD+ + H2O | - |
Klebsiella aerogenes | 5'-mercapto-5'-deoxyxanthosine 5'-phosphate + NADH | - |
? | |
1.1.1.205 | inosine 5'-phosphate + NAD+ + H2O | - |
Klebsiella aerogenes | xanthosine 5'-phosphate + NADH | - |
? | |
1.1.1.205 | inosine 5'-phosphorothioate + NAD+ + H2O | - |
Klebsiella aerogenes | xanthosine 5'-phosphorothioate + NADH | - |
? |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.205 | NAD+ | - |
Klebsiella aerogenes |