Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Collart, F.R.; Huberman, E.
    Cloning and sequence analysis of the human and Chinese hamster inosine-5-monophosphate dehydrogenase cDNAs (1988), J. Biol. Chem., 263, 15769-15772.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.205 Chinese hamster Cricetulus griseus
1.1.1.205 Chinese hamster Homo sapiens
1.1.1.205 human Cricetulus griseus
1.1.1.205 human Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.205 0.021
-
 IMP
-
 Cricetulus griseus
1.1.1.205 0.029
-
 NAD+
-
 Cricetulus griseus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.1.1.205 56000
-
-
 Homo sapiens
1.1.1.205 56000
-
 SDS-PAGE, two different proteins of identical molecular weight but differently charged Cricetulus griseus
1.1.1.205 56280
-
 calculated from amino acid sequence Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.205 Cricetulus griseus
-
 chinese hamster, MPA resistant VM2 variant cells
-
1.1.1.205 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.205
-
 Cricetulus griseus

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.1.1.205 1.08
-
-
 Cricetulus griseus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.205 inosine 5'-phosphate + NAD+ + H2O
-
 Cricetulus griseus xanthosine 5'-phosphate + NADH
-
 ?
1.1.1.205 inosine 5'-phosphate + NAD+ + H2O
-
 Homo sapiens xanthosine 5'-phosphate + NADH
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.205 NAD+
-
 Cricetulus griseus
1.1.1.205 NAD+
-
 Homo sapiens