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Literature summary extracted from
- Preparation and properties of adenylate cyclase from Escherichia coli (1974), Methods Enzymol., 38C, 155-160.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.6.1.1 | Ca2+ | - |
Escherichia coli |  |
| 4.6.1.1 | Ca2+ | - |
Glutamicibacter nicotianae | |
| 4.6.1.1 | Co2+ | high concentrations | Escherichia coli | |
| 4.6.1.1 | diphosphate | - |
Escherichia coli | |
| 4.6.1.1 | diphosphate | - |
Glutamicibacter nicotianae | |
| 4.6.1.1 | F- | - |
Escherichia coli | |
| 4.6.1.1 | F- | - |
Glutamicibacter nicotianae | |
| 4.6.1.1 | Mercuric acetate | - |
Escherichia coli | |
| 4.6.1.1 | Mercuric acetate | - |
Glutamicibacter nicotianae | |
| 4.6.1.1 | pyridoxal 5'-phosphate | - |
Escherichia coli | |
| 4.6.1.1 | pyridoxal 5'-phosphate | - |
Glutamicibacter nicotianae | |
| 4.6.1.1 | Ribonucleoside triphosphates | - |
Escherichia coli | |
| 4.6.1.1 | Ribonucleoside triphosphates | - |
Glutamicibacter nicotianae | |
| 4.6.1.1 | Zn2+ | - |
Escherichia coli | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 4.6.1.1 | 0.45 | - |
ATP | - |
Escherichia coli | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.6.1.1 | Mg2+ | - |
Escherichia coli | |
| 4.6.1.1 | Mg2+ | - |
Glutamicibacter nicotianae | |
| 4.6.1.1 | Mn2+ | - |
Escherichia coli | |
| 4.6.1.1 | Mn2+ | - |
Glutamicibacter nicotianae | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 4.6.1.1 | 92000 | 110000 | sucrose density gradient centrifugation | Escherichia coli |
| 4.6.1.1 | 92000 | 110000 | sucrose density gradient centrifugation | Glutamicibacter nicotianae |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.6.1.1 | Escherichia coli | - |
- |
- |
| 4.6.1.1 | Glutamicibacter nicotianae | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 4.6.1.1 | - |
Escherichia coli |
Storage Stability
| EC Number | Storage Stability | Organism |
|---|---|---|
| 4.6.1.1 | liquid N2, several months | Escherichia coli |
| 4.6.1.1 | liquid N2, several months | Glutamicibacter nicotianae |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.6.1.1 | ATP | - |
Escherichia coli | 3',5'-cAMP + diphosphate | - |
? | |
| 4.6.1.1 | ATP | - |
Glutamicibacter nicotianae | 3',5'-cAMP + diphosphate | - |
? | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 4.6.1.1 | 9 | - |
- |
Escherichia coli |
| 4.6.1.1 | 9 | - |
- |
Glutamicibacter nicotianae |
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Release 2023.1 (January 2023)
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