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Literature summary extracted from

  • Levasseur, S.; Friedman, Y.; Burke, G.
    Prostaglandin metabolism in the rat adrenal cortex: Characterization of prostaglandin-9-ketoreductase and 15-hydroxyprostaglandin dehydrogenase (1980), Biochem. Biophys. Res. Commun., 95, 236-242.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.197 NADPH
-
 Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.197 0.157
-
 prostaglandin E1
-
 Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.197 Homo sapiens
-
 human
-
1.1.1.197 Platyrrhini
-
-
-
1.1.1.197 Rattus norvegicus
-
 rat, Holtzman
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.197 adrenal cortex
-
 Rattus norvegicus
-
1.1.1.197 brain
-
 Homo sapiens
-
1.1.1.197 brain
-
 Platyrrhini
-
1.1.1.197 kidney
-
 Rattus norvegicus
-
1.1.1.197 lung
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.197 prostaglandin E1 + NADP+
-
 Rattus norvegicus 15-keto-prostaglandin E1 + NADPH + H+
-
 ?
1.1.1.197 prostaglandin E2 + NADPH + H+
-
 Platyrrhini prostaglandin F2 + NADP+
-
 ?
1.1.1.197 prostaglandin F + NADP+
-
 Rattus norvegicus ? + NADPH
-
 ?