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Literature summary extracted from

  • Ueda, M.; Tanaka, A.
    Long-chain alcohol dehydrogenase of Candida yeast (1990), Methods Enzymol., 188, 171-175.
    View publication on PubMed

General Stability

EC Number General Stability Organism
1.1.1.192 dithiothreitol, 2 mM, no stabilization, crude extract Yarrowia lipolytica
1.1.1.192 dithiothreitol, 2 mM, no stabilization, crude extract Candida tropicalis
1.1.1.192 ethylene glycol, 20% w/w, no stabilization, crude extract Yarrowia lipolytica
1.1.1.192 ethylene glycol, 20% w/w, no stabilization, crude extract Candida tropicalis
1.1.1.192 solubilization with 1% Tween 80 or Triton X-100 at 4°C stimulates inactivation, crude extract Yarrowia lipolytica
1.1.1.192 solubilization with 1% Tween 80 or Triton X-100 at 4°C stimulates inactivation, crude extract Candida tropicalis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.192 long-chain alcohol + NAD+ + H2O Yarrowia lipolytica peroxisomal enzyme is participating in fatty acid degradation long-chain carboxylate + NADH
-
 ?
1.1.1.192 long-chain alcohol + NAD+ + H2O Candida tropicalis peroxisomal enzyme is participating in fatty acid degradation long-chain carboxylate + NADH
-
 ?
1.1.1.192 long-chain alcohol + NAD+ + H2O Yarrowia lipolytica microsomal and mitochondrial enzyme may have an indispensable role in lipid biosynthesis long-chain carboxylate + NADH
-
 ?
1.1.1.192 long-chain alcohol + NAD+ + H2O Candida tropicalis microsomal and mitochondrial enzyme may have an indispensable role in lipid biosynthesis long-chain carboxylate + NADH
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.192 Candida tropicalis
-
-
-
1.1.1.192 Yarrowia lipolytica
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.192 long-chain alcohol + NAD+ + H2O C6-C18 alcohols Yarrowia lipolytica long-chain carboxylate + NADH
-
 ?
1.1.1.192 long-chain alcohol + NAD+ + H2O maximal activity with decanol Yarrowia lipolytica long-chain carboxylate + NADH
-
 ?
1.1.1.192 long-chain alcohol + NAD+ + H2O C17-C-19 alcohols do not serve as a good substrate Yarrowia lipolytica long-chain carboxylate + NADH
-
 ?
1.1.1.192 long-chain alcohol + NAD+ + H2O C17-C-19 alcohols do not serve as a good substrate Candida tropicalis long-chain carboxylate + NADH
-
 ?
1.1.1.192 long-chain alcohol + NAD+ + H2O C8-C16 Candida tropicalis long-chain carboxylate + NADH
-
 ?
1.1.1.192 long-chain alcohol + NAD+ + H2O peroxisomal enzyme is participating in fatty acid degradation Yarrowia lipolytica long-chain carboxylate + NADH
-
 ?
1.1.1.192 long-chain alcohol + NAD+ + H2O peroxisomal enzyme is participating in fatty acid degradation Candida tropicalis long-chain carboxylate + NADH
-
 ?
1.1.1.192 long-chain alcohol + NAD+ + H2O microsomal and mitochondrial enzyme may have an indispensable role in lipid biosynthesis Yarrowia lipolytica long-chain carboxylate + NADH
-
 ?
1.1.1.192 long-chain alcohol + NAD+ + H2O microsomal and mitochondrial enzyme may have an indispensable role in lipid biosynthesis Candida tropicalis long-chain carboxylate + NADH
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.1.1.192 30
-
 assay at Yarrowia lipolytica
1.1.1.192 30
-
 assay at Candida tropicalis

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.192 NAD+ absolute requirement Yarrowia lipolytica
1.1.1.192 NAD+ absolute requirement Candida tropicalis