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Literature summary extracted from

  • Lee, T.C.
    Characterization of fatty alcohol:NAD+ oxidoreductase from rat liver (1979), J. Biol. Chem., 254, 2892-2896.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.1.1.192 albumin 0.5 mg/ml increases reaction rate Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.192 cyanide
-
 Rattus norvegicus
1.1.1.192 additional information not: pyrazole, sodium azide, AMP, ATP, quinacrine, iodoacetate Rattus norvegicus
1.1.1.192 N-ethylmaleimide
-
 Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.192 0.00067
-
 hexadecanol
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.192 long-chain alcohol + NAD+ + H2O Rattus norvegicus enzyme may play an important role in regulating the cellular levels of ether-linked lipids long-chain carboxylate + NADH
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.192 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.192 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.192 hexadecanol + NAD+ + H2O
-
 Rattus norvegicus hexadecanal + NADH
-
 ?
1.1.1.192 long-chain alcohol + NAD+ + H2O maximal activity with decanol Rattus norvegicus long-chain carboxylate + NADH
-
 ?
1.1.1.192 long-chain alcohol + NAD+ + H2O C10-C18 Rattus norvegicus long-chain carboxylate + NADH
-
 ?
1.1.1.192 long-chain alcohol + NAD+ + H2O enzyme may play an important role in regulating the cellular levels of ether-linked lipids Rattus norvegicus long-chain carboxylate + NADH
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.1.1.192 37
-
 assay at Rattus norvegicus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.192 8.4
-
 hexadecanol, diphosphate buffer Rattus norvegicus
1.1.1.192 8.8 9 hexadecanol, glycine or barbital buffer Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.192 NAD+ absolute requirement Rattus norvegicus