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Literature summary extracted from
- Adenylate cyclase from Phycomyces sporangiophore (1980), Phytochemistry, 19, 1913-1918.
No PubMed abstract available
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.6.1.1 | catecholamine | activation | Phycomyces blakesleeanus |  |
| 4.6.1.1 | dopamine | activation | Phycomyces blakesleeanus | |
| 4.6.1.1 | epinephrin | activation | Phycomyces blakesleeanus | |
| 4.6.1.1 | GTP | activation | Phycomyces blakesleeanus | |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.6.1.1 | alloxan | - |
Phycomyces blakesleeanus | |
| 4.6.1.1 | ATP | high concentrations | Phycomyces blakesleeanus | |
| 4.6.1.1 | Ca2+ | - |
Phycomyces blakesleeanus | |
| 4.6.1.1 | Mn2+ | - |
Phycomyces blakesleeanus | |
| 4.6.1.1 | NaF | - |
Phycomyces blakesleeanus | |
| 4.6.1.1 | nucleotides | - |
Phycomyces blakesleeanus | |
| 4.6.1.1 | Ouabain | - |
Phycomyces blakesleeanus | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 4.6.1.1 | 0.5 | - |
ATP | - |
Phycomyces blakesleeanus | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 4.6.1.1 | membrane | - |
Phycomyces blakesleeanus | 16020 | - |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.6.1.1 | F- | - |
Phycomyces blakesleeanus | |
| 4.6.1.1 | Mg2+ | - |
Phycomyces blakesleeanus | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.6.1.1 | Phycomyces blakesleeanus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 4.6.1.1 | sporangiophore | - |
Phycomyces blakesleeanus | - |
Storage Stability
| EC Number | Storage Stability | Organism |
|---|---|---|
| 4.6.1.1 | -20°C, 3 weeks | Phycomyces blakesleeanus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.6.1.1 | ATP | - |
Phycomyces blakesleeanus | 3',5'-cyclic AMP + diphosphate | - |
? | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 4.6.1.1 | 7.5 | 8.2 | - |
Phycomyces blakesleeanus |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.6.1.1 | ADP | activation | Phycomyces blakesleeanus | |
| 4.6.1.1 | AMP | activation | Phycomyces blakesleeanus | |
| 4.6.1.1 | IMP | activation | Phycomyces blakesleeanus | |
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