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Literature summary extracted from

  • Thong, K.W.; Coombs, G.H.
    Trichomonas species: homocysteine desulphurase and serine sulphydrase activities (1987), Exp. Parasitol., 63, 143-151.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.4.1.2 2,2'-dithiodiethylanol
-
 Trichomonas vaginalis
4.4.1.2 2,4-Dichlorophenol
-
 Trichomonas vaginalis
4.4.1.2 bithionol
-
 Trichomonas vaginalis
4.4.1.2 Dichlorophene
-
 Trichomonas vaginalis
4.4.1.2 DL-propargylglycine
-
 Trichomonas vaginalis
4.4.1.2 Hexachlorophene
-
 Trichomonas vaginalis

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.4.1.2 0.549
-
 homocysteine
-
 Trichomonas vaginalis

Organism

EC Number Organism UniProt Comment Textmining
4.4.1.2 no activity in Trichomitus batrachorum
-
-
-
4.4.1.2 no activity in Trichomonas foetus
-
-
-
4.4.1.2 Pentatrichomonas hominis
-
-
-
4.4.1.2 Trichomonas vaginalis
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.4.1.2 L-homocysteine + H2O
-
 Trichomonas vaginalis H2S + NH3 + 2-oxobutanoate
-
 ?
4.4.1.2 L-homocysteine + H2O
-
 Pentatrichomonas hominis H2S + NH3 + 2-oxobutanoate
-
 ?