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Literature summary extracted from

  • Steegborn, C.; Clausen, T.; Sondermann, P.; Jacob, U.; Worbs, M.; Marinkovic, S.; Huber, R.; Wahl, M.C.
    Kinetics and inhibition of recombinant human cystathionine gamma-lyase. Toward the rational control of transsulfuration (1999), J. Biol. Chem., 274, 12675-12684.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.4.1.1 expression in Escherichia coli Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.4.1.1 aminoethoxyvinylglycine
-
Homo sapiens
4.4.1.1 propargylglycine
-
Homo sapiens
4.4.1.1 trifluoro-Ala
-
Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.4.1.1 0.5
-
L-cystathionine
-
Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
4.4.1.1 Homo sapiens
-
-
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.4.1.1 additional information
-
-
Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.4.1.1 L-cystathionine + H2O
-
Homo sapiens ?
-
?

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
4.4.1.1 1.9
-
cystathionine
-
Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.4.1.1 8.7
-
-
Homo sapiens

pH Range

EC Number pH Minimum pH Maximum Comment Organism
4.4.1.1 8 9 pH 8.0: about 85% of maximal activity, pH 9.0: about 50% of maximal activity Homo sapiens