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Literature summary extracted from
- gamma-Cystathionase of rat liver: effects of pyridoxal phosphate and other compounds on reaction rates (1975), Arch. Biochem. Biophys., 171, 378-384.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.4.1.1 | 5,5'-dithiobis(2-nitrobenzoate) | - |
Rattus norvegicus |  |
| 4.4.1.1 | additional information | the reaction of cystathionase with cystathionine and homoserine decreases rapidly with time. The reaction becomes inhibited, probably by the formation of a stable enzyme-bound intermediate. The inhibition can be partially relieved by pyridoxal 5'-phosphate, NaCl, alpha-keto acids, and other compounds. These agents prevent the inhibition by providing an environment that helps to decrease the nucleophilicity of the sulfhydryl | Rattus norvegicus |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.4.1.1 | Rattus norvegicus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 4.4.1.1 | liver | - |
Rattus norvegicus | - |
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Release 2023.1 (January 2023)
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