EC Number | General Stability | Organism |
---|---|---|
4.3.2.2 | stable to thawing and refreezing at a protein concentration of above 2 mg/ml | Rattus norvegicus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
4.3.2.2 | erythro-beta-fluoro-4-(N-succino)-5-aminoimidazole-4-carboxamide ribonucleotide | - |
Rattus norvegicus | |
4.3.2.2 | erythro-beta-fluoroadenylosuccinate | - |
Rattus norvegicus | |
4.3.2.2 | erythro-beta-fluoroaspartate | - |
Rattus norvegicus | |
4.3.2.2 | I- | 100-200 mM | Rattus norvegicus | |
4.3.2.2 | NO3- | 100-200 mM | Rattus norvegicus | |
4.3.2.2 | PO43- | activates at low concentration, inhibits at high concentrations above 25 mM | Rattus norvegicus | |
4.3.2.2 | SO42- | activates at low concentrations, inhibits at concentrations above 25 mM | Rattus norvegicus | |
4.3.2.2 | threo-beta-4-(N-succino)-5-aminoimidazole-4-carboxamide ribonucleotide | - |
Rattus norvegicus | |
4.3.2.2 | threo-beta-fluoroadenylosuccinate | - |
Rattus norvegicus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
4.3.2.2 | 0.001 | - |
4-(N-succino)-5-aminoimidazole-4-carboxamide ribonucleotide | - |
Rattus norvegicus | |
4.3.2.2 | 0.0015 | - |
N6-(1,2-dicarboxyethyl)AMP | - |
Rattus norvegicus |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
4.3.2.2 | PO43- | activates at low concentration, inhibits at high concentrations above 25 mM | Rattus norvegicus | |
4.3.2.2 | SO42- | activates at low concentrations, inhibits at concentrations above 25 mM | Rattus norvegicus |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
4.3.2.2 | 52000 | - |
4 * 52000, SDS-PAGE | Rattus norvegicus |
4.3.2.2 | 200000 | - |
gel filtration | Rattus norvegicus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.3.2.2 | 4-(N-succino)-5-aminoimidazole-4-carboxamide ribonucleotide | Rattus norvegicus | reaction in the biosynthesis of AMP | 5-aminoimidazole-4-carboxamide ribonucleotide + fumarate | - |
? | |
4.3.2.2 | N6-(1,2-dicarboxyethyl)AMP | Rattus norvegicus | reaction in the biosynthesis of AMP | fumarate + AMP | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.3.2.2 | Rattus norvegicus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
4.3.2.2 | - |
Rattus norvegicus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
4.3.2.2 | muscle | skeletal muscle | Rattus norvegicus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
4.3.2.2 | 11 | - |
- |
Rattus norvegicus |
EC Number | Storage Stability | Organism |
---|---|---|
4.3.2.2 | 4°C, stable for several weeks | Rattus norvegicus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.3.2.2 | 1-(5-phosphoribosyl)-4-(N-succinocarboxamide)-5-aminoimidazole | i.e. 4-(N-succino)-5-aminoimidazole-4-carboxamide ribonucleotide ? | Rattus norvegicus | 5'-phosphoribosyl-5-amino-4-imidazolecarboxamide + fumarate | - |
? | |
4.3.2.2 | 4-(N-succino)-5-aminoimidazole-4-carboxamide ribonucleotide | reaction in the biosynthesis of AMP | Rattus norvegicus | 5-aminoimidazole-4-carboxamide ribonucleotide + fumarate | - |
? | |
4.3.2.2 | N6-(1,2-dicarboxyethyl)AMP | i.e. adenylosuccinate | Rattus norvegicus | fumarate + AMP | - |
? | |
4.3.2.2 | N6-(1,2-dicarboxyethyl)AMP | reaction in the biosynthesis of AMP | Rattus norvegicus | fumarate + AMP | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
4.3.2.2 | tetramer | 4 * 52000, SDS-PAGE | Rattus norvegicus |