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Literature summary extracted from

  • Pridham, J.B.; Woodhead, S.
    Multimolecular forms of phenylalanine-ammonia lyase in Alternaria (1974), Biochem. Soc. Trans., 2, 1070-1072.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.3.1.24 4-coumarate inhibition of enzyme form PAL116, no inhibition of enzyme form PAL68 Alternaria sp.
4.3.1.24 benzoate uncompetitive inhibition of enzyme form PAL68, non-competitive inhibition of enzyme form PAL116 Alternaria sp.
4.3.1.24 Cinnamic acid enzyme form PAL116 is inhibited, no inhibition of enzyme form PAL68 Alternaria sp.
4.3.1.24 p-hydroxybenzoate inhibition of enzyme form PAL116, no inhibition of enzyme form P68 Alternaria sp.

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.3.1.24 0.5
-
 L-Phe
-
 Alternaria sp.
4.3.1.24 0.7
-
 L-Phe
-
 Alternaria sp.

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.3.1.24 380000
-
 enzyme form PAL116, gel filtration Alternaria sp.
4.3.1.24 560000
-
 enzyme form PAL68, gel filtration Alternaria sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.3.1.24 additional information Alternaria sp. key enzyme in the formation of a variety of phenolic compounds ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.3.1.24 Alternaria sp.
-
 2 different enzyme forms are isolated after 68 h and after 116 h: PAL68 and PAL116
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.3.1.24
-
 Alternaria sp.

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.3.1.24 mycelium 2 different enzyme forms are isolated after 68 h and after 116 h: PAL68 and PAL116 Alternaria sp.
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.3.1.24 L-Phe
-
 Alternaria sp. (E)-cinnamate + NH3
-
 ?
4.3.1.24 additional information key enzyme in the formation of a variety of phenolic compounds Alternaria sp. ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.3.1.24 8.2
-
 enzyme form PAL68 Alternaria sp.
4.3.1.24 8.8
-
 enzyme form PAL116 Alternaria sp.