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Literature summary extracted from
- Leucine 2,3-aminomutase, an enzyme of leucine catabolism (1976), J. Biol. Chem., 251, 1859-1863.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.4.3.7 | Intrinsic factors | - |
Clostridium sporogenes |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.4.3.7 | alpha-Leu | Rattus norvegicus | - |
? | - |
? |  |
| 5.4.3.7 | alpha-Leu | Clostridium sporogenes | initial step in the fermentation of Leu to acetate | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.4.3.7 | Chlorocebus aethiops | - |
- |
- |
| 5.4.3.7 | Clostridium cochlearium | - |
- |
- |
| 5.4.3.7 | Clostridium sporogenes | - |
- |
- |
| 5.4.3.7 | Gallus gallus | - |
no activity in chicken liver | - |
| 5.4.3.7 | Homo sapiens | - |
- |
- |
| 5.4.3.7 | Macaca mulatta | - |
- |
- |
| 5.4.3.7 | no activity in Canis familiaris | - |
- |
- |
| 5.4.3.7 | Ovis aries | - |
- |
- |
| 5.4.3.7 | Rattus norvegicus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 5.4.3.7 | leukocyte | - |
Homo sapiens | - |
| 5.4.3.7 | liver | - |
Homo sapiens | - |
| 5.4.3.7 | liver | - |
Ovis aries | - |
| 5.4.3.7 | liver | - |
Macaca mulatta | - |
| 5.4.3.7 | liver | - |
Chlorocebus aethiops | - |
| 5.4.3.7 | liver | no activity detected | Gallus gallus | - |
| 5.4.3.7 | liver | no activity detected | Rattus norvegicus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.4.3.7 | alpha-Leu | - |
Gallus gallus | beta-Leu | - |
? | |
| 5.4.3.7 | alpha-Leu | - |
Homo sapiens | beta-Leu | - |
? | |
| 5.4.3.7 | alpha-Leu | - |
Rattus norvegicus | beta-Leu | - |
? | |
| 5.4.3.7 | alpha-Leu | - |
Ovis aries | beta-Leu | - |
? | |
| 5.4.3.7 | alpha-Leu | - |
Macaca mulatta | beta-Leu | - |
? | |
| 5.4.3.7 | alpha-Leu | - |
Chlorocebus aethiops | beta-Leu | - |
? | |
| 5.4.3.7 | alpha-Leu | - |
Clostridium cochlearium | beta-Leu | - |
? | |
| 5.4.3.7 | alpha-Leu | r | Clostridium sporogenes | beta-Leu | i.e. 3-amino-4-methylpentanoate | ? | |
| 5.4.3.7 | alpha-Leu | - |
Rattus norvegicus | ? | - |
? | |
| 5.4.3.7 | alpha-Leu | initial step in the fermentation of Leu to acetate | Clostridium sporogenes | ? | - |
? | |
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