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Literature summary extracted from
- Lactate metabolism by Peptostreptococcus elsdenii: evidence for lactyl coenzyme A dehydrase (1965), Biochim. Biophys. Acta, 97, 202-213.
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.2.1.54 | Mg2+ | required | Megasphaera elsdenii |  |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 4.2.1.54 | 41000 | - |
enzyme consists of two proteins, EI and EII, neither of the two can catalyze the reaction alone, EI: 27000, EII: x * 41000 + x * 48000, SDS-PAGE | Megasphaera elsdenii |
| 4.2.1.54 | 48000 | - |
enzyme consists of two proteins, EI and EII, neither of the two can catalyze the reaction alone, EI: 27000, EII: x * 41000 + x * 48000, SDS-PAGE | Megasphaera elsdenii |
| 4.2.1.54 | 1000000 | - |
enzyme consists of two proteins, EI and EII, neither of the two can catalyze the reaction alone, EI: 27000 Da, EII: 10000000 Da, gel filtration | Megasphaera elsdenii |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.2.1.54 | lactoyl-CoA + H2O | Megasphaera elsdenii | enzyme in the pathway of propionate formation | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.2.1.54 | Megasphaera elsdenii | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 4.2.1.54 | partial | Megasphaera elsdenii |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.2.1.54 | acrylyl-CoA + H2O | - |
Megasphaera elsdenii | lactoyl-CoA | - |
? | |
| 4.2.1.54 | lactoyl-CoA + H2O | enzyme in the pathway of propionate formation | Megasphaera elsdenii | ? | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 4.2.1.54 | polymer | enzyme consists of two proteins, EI and EII, neither of the two can catalyze the reaction alone, EI: 27000, EII: x * 41000 + x * 48000, SDS-PAGE | Megasphaera elsdenii |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 4.2.1.54 | 8 | - |
- |
Megasphaera elsdenii |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.2.1.54 | ATP | required, no stoichiometric hydrolysis of ATP | Megasphaera elsdenii | |
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Release 2023.1 (January 2023)
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