Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Qin, Y.M.; Poutanen, M.H.; Helander, H.M.; Kvist, A.P.; Siivari, K.M.; Schmitz, W.; Conzelmann, E.; Hellman, U.; Hiltunen, J.K.
    Peroxisomal multifunctional enzyme of beta-oxidation metabolizing D-3-hydroxyacyl-CoA esters in rat liver: molecular cloning, expression and characterization (1997), Biochem. J., 321, 21-28.
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.35 Rattus norvegicus
-
 Wistar rat
-
1.1.1.36 Rattus norvegicus
-
 Wistar rat
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.1.1.35 4.17
-
 (S)-3-hydroxydecanoyl-CoA as substrate, activity of L-specific 3-hydroxyacyl-CoA dehydrogenase in perMFE-I Rattus norvegicus
1.1.1.35 4.22
-
 (S)-3-hydroxybutyryl-CoA as substrate, activity of L-specific 3-hydroxyacyl-CoA dehydrogenase in perMFE-I Rattus norvegicus
1.1.1.36 0.43
-
 (R)-3-hydroxybutyryl-CoA as substrate, activity of D-specific 3-hydroxyacyl-CoA dehydrogenase in perMFE-II Rattus norvegicus
1.1.1.36 0.58
-
 (R)-3-hydroxydecanoyl-CoA as substrate, activity of D-specific 3-hydroxyacyl-CoA dehydrogenase in perMFE-II Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.35 (S)-3-hydroxybutyryl-CoA + NAD+
-
 Rattus norvegicus 3-oxobutyryl-CoA + NADH + H+
-
 ?
1.1.1.35 (S)-3-hydroxydecanoyl-CoA + ?
-
 Rattus norvegicus 3-oxodecanoyl-CoA + NADH + H+
-
 ?
1.1.1.36 (R)-3-hydroxybutyryl-CoA + NAD+
-
 Rattus norvegicus 3-oxobutyryl-CoA + NADH + H+
-
 ?
1.1.1.36 (R)-3-hydroxydecanoyl-CoA + NAD+
-
 Rattus norvegicus 3-oxodecanoyl-CoA + NADH + H+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.35 L-specific 3-hydroxyacyl-CoA dehydrogenase
-
 Rattus norvegicus
1.1.1.36 D-specific 3-hydroxyacyl-CoA dehydrogenase
-
 Rattus norvegicus
4.2.1.119 2-enoyl-CoA hydratase 2 evidence that hydratase 2 can be either an integral part and/or a fragmentation product of a multifunctional beta-oxidation protein, perMFE-II Rattus norvegicus
4.2.1.119 hydratase 2
-
 Rattus norvegicus