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Literature summary extracted from

  • Plateau, P.; Mayaux, J.F.; Blanquet, S.
    Zinc(II)-dependent synthesis of diadenosine 5',5'''-P1,P4-tetraphosphate by Escherichia coli and yeast phenylalanyl transfer ribonucleic acid synthetases (1981), Biochemistry, 20, 4654-4662.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.1.1.20 Zn2+ inhibition of tRNAPhe aminoacylation, required for conversion of ATP into diadenosine 5',5'''-P1,P4-tetraphosphate Escherichia coli
6.1.1.20 Zn2+ inhibition of tRNAPhe aminoacylation, required for conversion of ATP into diadenosine 5',5'''-P1,P4-tetraphosphate Saccharomyces cerevisiae

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
6.1.1.20 Zn2+ required for conversion of ATP into diadenosine 5',5'''-P1,P4-tetraphosphate Escherichia coli
6.1.1.20 Zn2+ required for conversion of ATP into diadenosine 5',5'''-P1,P4-tetraphosphate Saccharomyces cerevisiae
6.1.1.20 Zn2+ inhibition of tRNAPhe aminoacylation Escherichia coli
6.1.1.20 Zn2+ inhibition of tRNAPhe aminoacylation Saccharomyces cerevisiae

Organism

EC Number Organism UniProt Comment Textmining
6.1.1.20 Escherichia coli
-
-
-
6.1.1.20 Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.1.1.20 ATP + L-phenylalanine + tRNAPhe
-
Escherichia coli AMP + diphosphate + L-phenylalanyl-tRNAPhe
-
?
6.1.1.20 ATP + L-phenylalanine + tRNAPhe
-
Saccharomyces cerevisiae AMP + diphosphate + L-phenylalanyl-tRNAPhe
-
?
6.1.1.20 additional information synthesis of diadenosine 5',5'''-P1,P4-tetraphosphate Escherichia coli ?
-
?
6.1.1.20 additional information synthesis of diadenosine 5',5'''-P1,P4-tetraphosphate Saccharomyces cerevisiae ?
-
?