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Literature summary extracted from
- The mechanism of 6-phosphogluconic dehydrase (1964), J. Biol. Chem., 239, 3505-3510.
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.2.1.12 | Pseudomonas fluorescens | - |
A3.12 | - |
| 4.2.1.12 | Pseudomonas fluorescens A3.12 | - |
A3.12 | - |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 4.2.1.12 | - |
Pseudomonas fluorescens |
Reaction
| EC Number | Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|---|
| 4.2.1.12 | 6-phospho-D-gluconate = 2-dehydro-3-deoxy-6-phospho-D-gluconate + H2O | mechanism: 6-phosphogluconate is dehydrated to form enol-2-keto-3-deoxy-6-phosphogluconate, which is spontaneously ketonized | Pseudomonas fluorescens |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 4.2.1.12 | additional information | - |
coupled reaction of EC 4.2.1.12 plus EC 4.1.2.14 | Pseudomonas fluorescens |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.2.1.12 | 6-phospho-D-gluconate | - |
Pseudomonas fluorescens | 6-phospho-2-dehydro-3-deoxy-D-gluconate + H2O | - |
? |  |
| 4.2.1.12 | 6-phospho-D-gluconate | - |
Pseudomonas fluorescens A3.12 | 6-phospho-2-dehydro-3-deoxy-D-gluconate + H2O | - |
? | |
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Release 2023.1 (January 2023)
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