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Literature summary extracted from
- 6-Phosphoglucponic and related dehydrases (1971), The Enzymes, 3rd Ed. (Boyer, P. D. , ed. ), 5, 573-586.
No PubMed abstract available
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 4.2.1.12 | 0.6 | - |
6-phosphogluconate | - |
Pseudomonas putida |  |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.2.1.12 | Fe2+ | completely inactive in absence of divalent metal ion, Fe2+ is most effective | Pseudomonas putida | |
| 4.2.1.12 | Mg2+ | completely inactive in absence of divalent metal ion, 45% of the activation by Fe2+ | Pseudomonas putida | |
| 4.2.1.12 | Mn2+ | completely inactive in absence of divalent metal ion, 70% of the activation by Fe2+ | Pseudomonas putida | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.2.1.12 | 6-phospho-D-gluconate | Pseudomonas putida | - |
? | - |
? | |
| 4.2.1.12 | 6-phospho-D-gluconate | Pelomonas saccharophila | - |
? | - |
? | |
| 4.2.1.12 | 6-phospho-D-gluconate | Pseudomonas mildenbergii | - |
? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.2.1.12 | Pelomonas saccharophila | - |
- |
- |
| 4.2.1.12 | Pseudomonas mildenbergii | - |
- |
- |
| 4.2.1.12 | Pseudomonas putida | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.2.1.12 | 6-phospho-D-gluconate | - |
Pseudomonas putida | 6-phospho-2-dehydro-3-deoxy-D-gluconate + H2O | - |
ir | |
| 4.2.1.12 | 6-phospho-D-gluconate | - |
Pelomonas saccharophila | 6-phospho-2-dehydro-3-deoxy-D-gluconate + H2O | - |
? | |
| 4.2.1.12 | 6-phospho-D-gluconate | - |
Pseudomonas mildenbergii | 6-phospho-2-dehydro-3-deoxy-D-gluconate + H2O | - |
? | |
| 4.2.1.12 | 6-phospho-D-gluconate | - |
Pseudomonas putida | ? | - |
? | |
| 4.2.1.12 | 6-phospho-D-gluconate | - |
Pelomonas saccharophila | ? | - |
? | |
| 4.2.1.12 | 6-phospho-D-gluconate | - |
Pseudomonas mildenbergii | ? | - |
? | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 4.2.1.12 | 6.7 | 8 | - |
Pseudomonas putida |
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