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Literature summary extracted from

  • Merkulova, T.; Lucas, M.; Jabet, C.; Lamande, N.; Rouzeau, J.D.; Gros, F.; Lazar, M.; Keller, A.
    Biochemical characterization of the mouse muscle-specific enolase: developmental changes in electrophoretic variants and selective binding to other proteins (1997), Biochem. J., 323, 791-800.
    View publication on PubMedView publication on EuropePMC

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.2.1.11 0.078
-
 2-phospho-D-glycerate
-
 Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.2.1.11 2-phospho-D-glycerate Mus musculus beta,beta-enolase binds with high affinity the adjacent enzymes in the glycolytic pathway (pyruvate kinase and phosphoglycerate mutase), beta,beta-enolase binds with high affinity sarcomeric troponin but not actin and tropomyosin ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.11 Mus musculus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.2.1.11 beta,beta-enolase Mus musculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.2.1.11 additional information the embryonic alpha,alpha isoform remains distributed in many adult cell types, wheras a transition towards beta,beta-isoform and gamma,gamma-isoform occurs in striated muscle cells and neurons respectively Mus musculus
-
4.2.1.11 muscle hindlimb muscle Mus musculus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.2.1.11 additional information
-
-
 Mus musculus

Storage Stability

EC Number Storage Stability Organism
4.2.1.11 -74°C, pH 7.0, stable for up to 10 months, provided that multiple freezing and thawing steps are avoided Mus musculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.1.11 2-phospho-D-glycerate
-
 Mus musculus phosphoenolpyruvate
-
 ?
4.2.1.11 2-phospho-D-glycerate beta,beta-enolase binds with high affinity the adjacent enzymes in the glycolytic pathway (pyruvate kinase and phosphoglycerate mutase), beta,beta-enolase binds with high affinity sarcomeric troponin but not actin and tropomyosin Mus musculus ?
-
 ?
4.2.1.11 2-phospho-D-glycerate
-
 Mus musculus phosphoenolpyruvate + H2O
-
 ?