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Literature summary extracted from
- Purification, molecular properties and ontogeny of carbonic anhydrase isozymes. Evidence for A, B and C isozymes in avian and mammalian tissues (1977), Eur. J. Biochem., 78, 511-520.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.2.1.1 | acetazolamide | carbonic anhydrase A is 100times less sensitive than carbonic anhydrase C; carbonic anhydrase A is completely inhibited at 1 mM, carbonic anhydrase C is completely inhibited at 0.01 mM | Gallus gallus |  |
| 4.2.1.1 | acetazolamide | - |
Ovis aries | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.2.1.1 | Zinc | - |
Gallus gallus | |
| 4.2.1.1 | Zinc | contains 0.81 gatom of zinc per mol of enzyme, carbonic anhydrase A | Ovis aries | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 4.2.1.1 | 30000 | - |
x * 30000, carbonic anhydrase A, B and C, SDS-PAGE | Gallus gallus |
| 4.2.1.1 | 34000 | - |
carbonic anhydrase A, gel filtration | Ovis aries |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.2.1.1 | Gallus gallus | - |
- |
- |
| 4.2.1.1 | Ovis aries | - |
ovis aries | - |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 4.2.1.1 | cecum | carbonic anhydrase appears within 2 days of birth | Gallus gallus | - |
| 4.2.1.1 | erythrocyte | carbonic anhydrase B and C | Gallus gallus | - |
| 4.2.1.1 | erythrocyte | carbonic anhydrase B and C | Ovis aries | - |
| 4.2.1.1 | intestine | carbonic anhydrase B and C | Gallus gallus | - |
| 4.2.1.1 | intestine | carbonic anhydrase B and C | Ovis aries | - |
| 4.2.1.1 | muscle | carbonic anhydrase A | Gallus gallus | - |
| 4.2.1.1 | muscle | carbonic anhydrase A | Ovis aries | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.2.1.1 | CO2 + H2O | - |
Gallus gallus | H2CO3 | - |
? | |
| 4.2.1.1 | CO2 + H2O | - |
Ovis aries | H2CO3 | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 4.2.1.1 | ? | - |
Ovis aries |
| 4.2.1.1 | ? | x * 30000, carbonic anhydrase A, B and C, SDS-PAGE | Gallus gallus |
| 4.2.1.1 | monomer | - |
Gallus gallus |
| 4.2.1.1 | monomer | 1 * 34000, SDS-PAGE | Ovis aries |
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