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Literature summary extracted from

  • Hammer-Jespersen, K.; Munch-Petersen, A.
    Phosphodeoxyribomutase from Escherichia coli. Purification and some properties (1970), Eur. J. Biochem., 17, 397-407.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
5.4.2.7 Deoxyribose-1,5-diphosphate 10fold stimulation, Km: 0.00017 mM, optimal concentration: 0.0014 mM Escherichia coli
5.4.2.7 glucose 1,6-diphosphate 3fold stimulation, Km: 0.00008 mM, optimal concentration: 0.0007 mM Escherichia coli
5.4.2.7 ribose-1,5-diphosphate 10fold stimulation, Km: 0.00017 mM, optimal concentration: 0.0014 mM Escherichia coli

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.4.2.7 Ca2+ in presence of 0.2 mM CoCl2 Escherichia coli
5.4.2.7 Cd2+ in presence of 0.2 mM CoCl2 Escherichia coli
5.4.2.7 Cu2+ in presence of 0.2 mM CoCl2 Escherichia coli
5.4.2.7 Fe3+ in presence of 0.2 mM CoCl2 Escherichia coli
5.4.2.7 phosphate 50 mM, 95% inhibition Escherichia coli
5.4.2.7 SO42- 50 mM, 85% inhibition Escherichia coli
5.4.2.7 Zn2+ in presence of 0.2 mM CoCl2 Escherichia coli

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
5.4.2.7 0.013
-
deoxyribose 1-phosphate
-
Escherichia coli
5.4.2.7 0.043
-
ribose 1-phosphate
-
Escherichia coli

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
5.4.2.7 Co2+ activity is dependent on Mn2+, Ni2+ or Co2+. Optimal concentration: 0.05-0.06 mM Escherichia coli
5.4.2.7 Mn2+ activity is dependent on Mn2+, Ni2+ or Co2+. Optimal concentration: 0.05-0.06 mM Escherichia coli
5.4.2.7 Ni2+ activity is dependent on Mn2+, Ni2+ or Co2+. Optimal concentration: 0.05 mM with deoxyribose 1-phosphate and 0.09 mM with ribose 1-phosphate as substrate Escherichia coli

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
5.4.2.7 32000
-
gel filtration Escherichia coli
5.4.2.7 43000
-
1 * 43000, enzyme form I, II and III, SDS-PAGE Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
5.4.2.7 Escherichia coli
-
K12, mutant dra-thy-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
5.4.2.7
-
Escherichia coli

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
5.4.2.7 15.5
-
-
Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.4.2.7 D-ribose 1-phosphate
-
Escherichia coli D-ribose 5-phosphate
-
?
5.4.2.7 Deoxyribose 1-phosphate
-
Escherichia coli Deoxyribose 5-phosphate
-
?

Subunits

EC Number Subunits Comment Organism
5.4.2.7 monomer 1 * 43000, enzyme form I, II and III, SDS-PAGE Escherichia coli

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
5.4.2.7 8
-
-
Escherichia coli