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Literature summary extracted from
- Studies on the substrate specificity of acylneuraminate pyruvate-lyase (1971), Hoppe-Seyler's Z. Physiol. Chem., 352, 1073-1080.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.1.3.3 | N-Acetyl-4-oxo-D-neuraminic acid | - |
Clostridium perfringens |  |
| 4.1.3.3 | N-Monofluoroacetylneuraminic acid | - |
Clostridium perfringens | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 4.1.3.3 | 1.75 | - |
N-Formylneuraminic acid | - |
Clostridium perfringens | |
| 4.1.3.3 | 1.8 | - |
N-acetylneuraminic acid | - |
Clostridium perfringens | |
| 4.1.3.3 | 1.93 | - |
N-Succinylneuraminic acid | - |
Clostridium perfringens | |
| 4.1.3.3 | 2 | - |
N-Acetyl-8-O-acetylneuraminic acid | - |
Clostridium perfringens | |
| 4.1.3.3 | 2.2 | - |
N-glycolylneuraminic acid | - |
Clostridium perfringens | |
| 4.1.3.3 | 2.7 | - |
N-Monochloracetylneuraminic acid | - |
Clostridium perfringens | |
| 4.1.3.3 | 3.9 | - |
N-acetylneuraminic acid | - |
Clostridium perfringens | |
| 4.1.3.3 | 4.5 | - |
N-Acetyl-7-O-acetylneuraminic acid | - |
Clostridium perfringens | |
| 4.1.3.3 | 10 | - |
N-Monofluoracetylneuraminic acid | - |
Clostridium perfringens | |
| 4.1.3.3 | 12.5 | - |
N-acetyl-4-O-acetylneuraminic acid | - |
Clostridium perfringens | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.1.3.3 | Clostridium perfringens | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.1.3.3 | Methoxyneuraminic acid | - |
Clostridium perfringens | ? | - |
? | |
| 4.1.3.3 | N,O-Diacetylneuramininic acid | - |
Clostridium perfringens | ? | - |
? | |
| 4.1.3.3 | N-Acetyl-4-O-acetylneuraminic acid | - |
Clostridium perfringens | ? | - |
? | |
| 4.1.3.3 | N-Acetyl-7-O-acetylneuraminic acid | - |
Clostridium perfringens | ? | - |
? | |
| 4.1.3.3 | N-Acetyl-8-O-acetylneuraminic acid | - |
Clostridium perfringens | ? | - |
? | |
| 4.1.3.3 | N-Formylneuraminic acid | - |
Clostridium perfringens | ? | - |
? | |
| 4.1.3.3 | N-Glycolylneuraminic acid | - |
Clostridium perfringens | ? | - |
? | |
| 4.1.3.3 | N-Monochloracetylneuraminic acid | - |
Clostridium perfringens | ? | - |
? | |
| 4.1.3.3 | N-Monofluoracetylneuraminic acid | - |
Clostridium perfringens | ? | - |
? | |
| 4.1.3.3 | N-Succinylneuraminic acid | - |
Clostridium perfringens | ? | - |
? | |
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