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Literature summary extracted from
- Isocitrate lyase from a thermophilic Bacillus: effect of salts on enzyme activity (1973), J. Bacteriol., 116, 1160-1169.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.1.3.1 | KCl | at pH-values above 8.6 inhibition, below pH 8.6 activation by KCl | Bacillus sp. (in: Bacteria) |  |
| 4.1.3.1 | NaCl | activation by NaCl | Bacillus sp. (in: Bacteria) | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.1.3.1 | Mg2+ | - |
Bacillus sp. (in: Bacteria) | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.1.3.1 | Bacillus sp. (in: Bacteria) | - |
thermophilic | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.1.3.1 | isocitrate | - |
Bacillus sp. (in: Bacteria) | succinate + glyoxylate | - |
r | |
Temperature Stability [°C]
| EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 4.1.3.1 | additional information | - |
KCl, MgCl2, CaCl2 stabilize | Bacillus sp. (in: Bacteria) |
| 4.1.3.1 | 55.5 | - |
50% activity lost after 43 min, in presence of 0.4 M KCl 50% activity lost after 129 min | Bacillus sp. (in: Bacteria) |
| 4.1.3.1 | 60 | - |
50% activity lost after 5 min, in presence of 0.4 M KCl 50% activity lost after 4 min | Bacillus sp. (in: Bacteria) |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 4.1.3.1 | 7.5 | - |
presence of 0.3 M KCl | Bacillus sp. (in: Bacteria) |
| 4.1.3.1 | 8 | - |
absence of KCl | Bacillus sp. (in: Bacteria) |
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