BRENDA - Enzyme Database

Inhibition of isocitrate lyase by 3-nitropropionate, a reaction-intermediate analogue

Schloss, J.V.; Cleland, W.W.; Biochemistry 21, 4420-4427 (1982)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
4.1.3.1
3-nitropropionate
-
Vogesella indigofera
4.1.3.1
Maleate
-
Vogesella indigofera
4.1.3.1
methylenesuccinate
-
Vogesella indigofera
KM Value [mM]
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
4.1.3.1
1.1
-
succinate
-
Vogesella indigofera
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
4.1.3.1
isocitrate
Vogesella indigofera
glyoxylate cycle
?
-
-
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
4.1.3.1
Vogesella indigofera
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.1.3.1
isocitrate
-
33126
Vogesella indigofera
succinate + glyoxylate
-
33126
Vogesella indigofera
r
4.1.3.1
isocitrate
glyoxylate cycle
33126
Vogesella indigofera
?
-
-
-
-
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
4.1.3.1
3-nitropropionate
-
Vogesella indigofera
4.1.3.1
Maleate
-
Vogesella indigofera
4.1.3.1
methylenesuccinate
-
Vogesella indigofera
KM Value [mM] (protein specific)
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
4.1.3.1
1.1
-
succinate
-
Vogesella indigofera
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
4.1.3.1
isocitrate
Vogesella indigofera
glyoxylate cycle
?
-
-
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.1.3.1
isocitrate
-
33126
Vogesella indigofera
succinate + glyoxylate
-
33126
Vogesella indigofera
r
4.1.3.1
isocitrate
glyoxylate cycle
33126
Vogesella indigofera
?
-
-
-
-