Literature summary extracted from

Rosa, R.; Blouquit, Y.; Calvin, M.C.; Prome, D.; Prome, J.C.; Rosa, J.
Isolation, characterization, and structure of a mutant 89 ARG->Cys bisphosphoglycerate mutase. Implication of the active site in the mutation (1989), J. Biol. Chem., 264, 7837-7843.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
5.4.2.4	expression in Escherichia coli	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
5.4.2.4	Homo sapiens	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
5.4.2.4	mutant Arg89Cys	Homo sapiens

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
5.4.2.4	erythrocyte	-	Homo sapiens	-

Specific Activity [micromol/min/mg]

EC Number	Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
5.4.2.4	additional information	-	-	Homo sapiens

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5.4.2.4	1,3-Diphosphoglycerate	the enzyme has additional activities of EC 5.4.2.1(phosphoglycerate mutase) and EC 3.1.3.13 (bisphosphoglycerate phosphatase)	Homo sapiens	2,3-Diphosphoglycerate	-	?

Temperature Stability [°C]

EC Number	Temperature Stability Minimum [°C]	Temperature Stability Maximum [°C]	Comment	Organism
5.4.2.4	55	-	mutant Arg89Cys unstable, protection by 0.5 mM 2,3-diphosphoglycerate or, to a lesser degree by 4 mM 3-phosphoglycerate or 2-phosphoglycerate	Homo sapiens

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Release 2023.1 (January 2023)