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Literature summary extracted from

  • Cheng, P.W.; Carlson, D.M.
    Mechanism of phosphoacetylglucosamine mutase (1979), J. Biol. Chem., 254, 8353-8357.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
5.4.2.3 glucose 1,6-diphosphate required for reaction with glucose 1-phosphate, Km: 0.025 mM Sus scrofa
5.4.2.3 N-Acetylglucosamine 1,6-diphosphate required for reaction with N-acetylglucosamine 1-phosphate Sus scrofa

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
5.4.2.3 0.0237
-
 N-acetylglucosamine 1-phosphate
-
 Sus scrofa
5.4.2.3 0.658
-
 glucose 1-phosphate
-
 Sus scrofa

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
5.4.2.3 phosphate covalently linked to the enzyme. The phosphate-protein linkage is stable in mild acid, at 50 C for up to 2 h. However phosphate is completely released under mild alkaline conditions at 50 C within 1 h Sus scrofa

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
5.4.2.3 59000
-
 gel filtration Sus scrofa
5.4.2.3 64000
-
 1 * 64000, SDS-PAGE Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
5.4.2.3 Sus scrofa
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
5.4.2.3 N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate ping-pong mechanism Sus scrofa
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.4.2.3 submandibular gland
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.4.2.3 Glucose 1-phosphate in presence of glucose 1,6-diphosphate Sus scrofa Glucose 6-phosphate
-
 ?
5.4.2.3 N-Acetyl-D-glucosamine 1-phosphate in presence of N-acetylglucosamine 1,6-diphosphate Sus scrofa N-Acetyl-D-glucosamine 6-phosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
5.4.2.3 monomer 1 * 64000, SDS-PAGE Sus scrofa

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
5.4.2.3 additional information
-
 enzyme is present in two forms of different heat stability Sus scrofa