Any feedback?
Literature summary extracted from
- Isoenzymes of phosphoglucomutase from human blood cells: isolation and kinetic properties (1989), Prep. Biochem., 19, 251-271.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.4.2.2 | alpha-D-glucose 1,6-diphosphate | Km: 0.00077-0.00163 mM | Homo sapiens |  |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 5.4.2.2 | 0.057 | 0.062 | alpha-D-glucose 1-phosphate | isozyme PGM2 | Homo sapiens | |
| 5.4.2.2 | 0.0805 | 0.088 | alpha-D-glucose 1-phosphate | isozyme PGM1 | Homo sapiens | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.4.2.2 | Mg2+ | Km: 0.020 mM | Homo sapiens | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 5.4.2.2 | 58500 | - |
isozyme PGM1, gel filtration, SDS-PAGE | Homo sapiens |
| 5.4.2.2 | 69000 | - |
isozyme PGM2, gel filtration, SDS-PAGE | Homo sapiens |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.4.2.2 | Homo sapiens | - |
human | - |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 5.4.2.2 | isozymes PGM1 and PGM2 | Homo sapiens |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 5.4.2.2 | erythrocyte | - |
Homo sapiens | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 5.4.2.2 | 42 | - |
isozyme PGM2, substrate glucose 1-phosphate | Homo sapiens |
| 5.4.2.2 | 1263 | - |
isozyme PGM1, substrate glucose 1-phosphate | Homo sapiens |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.4.2.2 | alpha-D-glucose 1-phosphate | - |
Homo sapiens | alpha-D-glucose 6-phosphate | - |
? | |
| 5.4.2.2 | alpha-D-glucose 1-phosphate | - |
Homo sapiens | D-glucose 6-phosphate | - |
? | |
| 5.4.2.2 | additional information | isozyme PGM2 also displays activities of phosphoribomutase and glucose 1,6-bisphosphate synthase | Homo sapiens | ? | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 5.4.2.2 | monomer | 1 * 69000, isozyme PGM1, SDS-PAGE | Homo sapiens |
| 5.4.2.2 | monomer | 1 * 58500, isozyme PGM1, SDS-PAGE | Homo sapiens |
Temperature Stability [°C]
| EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 5.4.2.2 | 52 | - |
isozyme PGM2, 15 min, 55% loss of activity | Homo sapiens |
| 5.4.2.2 | 52 | - |
isozyme PGM1, 15 min, 90% loss of activity | Homo sapiens |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 5.4.2.2 | 8 | - |
isozymes PGM1 and PGM2 | Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
