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Literature summary extracted from

  • Watabe, K.; Freese, E.
    Purification and properties of the manganese-dependent phosphoglycerate mutase of Bacillus subtilis (1979), J. Bacteriol., 137, 773-778.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
5.4.2.12 2,3-diphosphoglycerate no cofactor Bacillus subtilis
5.4.2.12 additional information no influence on activity: DL-sulfolactate, L-sulfolactate, dihydroxyacetone phosphate, DL-glycerate, DL-alpha-glycerophosphate, 3-hydroxypropionate, L-lactate, 3-mercaptopropionate, 2-mercaptopropionate, phosphoenolpyruvate, O-phosphoserine, DL-o-phosphothreonine, propionate Bacillus subtilis

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.4.2.12 2,3-Butanedione
-
 Bacillus subtilis
5.4.2.12 Cd2+
-
 Bacillus subtilis
5.4.2.12 Cu2+
-
 Bacillus subtilis
5.4.2.12 EDTA
-
 Bacillus subtilis
5.4.2.12 Hg2+
-
 Bacillus subtilis
5.4.2.12 additional information no influence on activity: DL-sulfolactate, L-sulfolactate, dihydroxyacetone phosphate, DL-glycerate, DL-alpha-glycerophosphate, 3-hydroxypropionate, L-lactate, 3-mercaptopropionate, 2-mercaptopropionate, phosphoenolpyruvate, O-phosphoserine, DL-o-phosphothreonine, propionate, Li+, Ca2+, Co2+, Mg2+, Fe3+, Cr3+ Bacillus subtilis
5.4.2.12 Ni2+
-
 Bacillus subtilis
5.4.2.12 Pb2+
-
 Bacillus subtilis
5.4.2.12 Zn2+
-
 Bacillus subtilis

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
5.4.2.12 1.1
-
 3-phosphoglycerate
-
 Bacillus subtilis
5.4.2.12 1.47
-
 2-phosphoglycerate
-
 Bacillus subtilis

Organism

EC Number Organism UniProt Comment Textmining
5.4.2.12 Bacillus subtilis
-
-
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
5.4.2.12 621
-
-
 Bacillus subtilis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.4.2.12 2-Phosphoglycerate
-
 Bacillus subtilis 3-Phosphoglycerate
-
 ?
5.4.2.12 3-Phosphoglycerate
-
 Bacillus subtilis 2-Phosphoglycerate
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
5.4.2.12 7.5 7.8
-
 Bacillus subtilis

pH Range

EC Number pH Minimum pH Maximum Comment Organism
5.4.2.12 6 8.1
-
 Bacillus subtilis