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Literature summary extracted from

  • Creminon, C.; Rholam, M.; Boussetta, H.; Marrakchi, N.; Cohen, P.
    Synthetic peptide substrates as models to study a pro-ocytocin/neurophysin converting enzyme (1988), J. Chromatogr., 440, 439-448.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.62 [D-Arg12]-Pro-oxytocin/neurophysin(1-20) peptide I as substrate Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.62 Bos taurus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.24.62 partial Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.62 hypophysis pituitary neurosecretory granule Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.62 additional information No substrates are Nle11 or Nle12 Bos taurus ?
-
 ?
3.4.24.62 additional information No substrates are Ala9, Val7 Bos taurus ?
-
 ?
3.4.24.62 additional information No substrates are D-Lys11 Bos taurus ?
-
 ?
3.4.24.62 additional information No substrates are pro-oxytocin/neurophysin peptides (i.e. pro-OT/Np(1-20)) with D-Arg12 Bos taurus ?
-
 ?
3.4.24.62 Pro-oxytocin/neurophysin(1-20) + H2O strictly selective for basic amino acid doublet Lys11-Arg12, cleavage site: Arg12-Ala13 Bos taurus Pro-oxytocin/neurophysin(1-12) + pro-oxytocin/neurophysin(13-20)
-
 ?
3.4.24.62 Pro-oxytocin/neurophysin(1-20) + H2O i.e. model substrate peptide I Bos taurus Pro-oxytocin/neurophysin(1-12) + pro-oxytocin/neurophysin(13-20)
-
 ?
3.4.24.62 [Ala10]-Pro-oxytocin/neurophysin(1-20) + H2O
-
 Bos taurus ?
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.4.24.62 37
-
 assay at Bos taurus