EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.24.61 | bestatin | strong, 0.05 mM | Rattus norvegicus | |
3.4.24.61 | Ca2+ | 1 mM | Rattus norvegicus | |
3.4.24.61 | Chelating agents | strong | Rattus norvegicus | |
3.4.24.61 | Co2+ | 1 mM; strong | Rattus norvegicus | |
3.4.24.61 | Cu2+ | 1 mM; strong | Rattus norvegicus | |
3.4.24.61 | EDTA | 10 mM | Rattus norvegicus | |
3.4.24.61 | EGTA | 10 mM | Rattus norvegicus | |
3.4.24.61 | additional information | diisopropyl fluorophosphate (6 mM); Mg2+ (1 mM | Rattus norvegicus | |
3.4.24.61 | Zn2+ | 1 mM; strong | Rattus norvegicus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.24.61 | Rattus norvegicus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.4.24.61 | partial | Rattus norvegicus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.4.24.61 | brain | - |
Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.24.61 | additional information | [Tyr18]-pro-oxytocin/neurophysin-(1-18)-NH2, Pro-Glu-D-Arg-Lys-Tyr-NH2, Pro-Glu-Arg-D-Lys-Tyr-NH2 | Rattus norvegicus | ? | - |
? | |
3.4.24.61 | Pro-Gln-Arg-Lys-Tyr-NH2 + H2O | - |
Rattus norvegicus | Pro-Gln + Arg-Lys-Tyr-NH2 | - |
? | |
3.4.24.61 | Pro-Glu-Arg-Arg-Tyr-NH2 + H2O | - |
Rattus norvegicus | Pro-Glu + Arg-Arg-Tyr-NH2 | - |
? | |
3.4.24.61 | Pro-Gly-Arg-Lys-Tyr-NH2 + H2O | - |
Rattus norvegicus | Pro-Gly + Arg-Lys-Tyr-NH2 | - |
? | |
3.4.24.61 | Somatostatin-28 + H2O | cleavage on amino side of Arg-Lys doublet | Rattus norvegicus | Somatostatin-28-(13-28) + somatostatin-28-(1-12) | - |
? | |
3.4.24.61 | Somatostatin-28 + H2O | cleavage site: Glu12-+-Arg13-Lys14, the term -+- depicts the point of cleavage | Rattus norvegicus | Somatostatin-28-(13-28) + somatostatin-28-(1-12) | - |
? | |
3.4.24.61 | Somatostatin-28 + H2O | i.e. octacosapeptide | Rattus norvegicus | Somatostatin-28-(13-28) + somatostatin-28-(1-12) | - |
? | |
3.4.24.61 | [Ala17,Tyr20]-Somatostatin-28-(10-20)-NH2 + H2O | i.e. model peptide I | Rattus norvegicus | Pro-Arg-Glu + Arg-Lys-Ala-Gly-Ala-Lys-Asn-Tyr-NH2 | - |
? | |
3.4.24.61 | [Ala17,Tyr20]-Somatostatin-28-(10-20)-NH2 + H2O | i.e. Pro-Arg-Glu-Arg-Lys-Ala-Gly-Ala-Lys-Asn-Tyr-NH2 | Rattus norvegicus | Pro-Arg-Glu + Arg-Lys-Ala-Gly-Ala-Lys-Asn-Tyr-NH2 | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.4.24.61 | More | endopeptidase of somatostatin-28 convertase complex | Rattus norvegicus |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
3.4.24.61 | 37 | - |
assay at | Rattus norvegicus |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.4.24.61 | 8.5 | - |
peptide I as substrate | Rattus norvegicus |
EC Number | pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|---|
3.4.24.61 | 7.3 | 9 | about half-maximal activity at pH 7.3 and about 90% of maximal activity at pH 9, peptide I as substrate | Rattus norvegicus |
3.4.24.61 | 8 | 9 | - |
Rattus norvegicus |
EC Number | pH Stability | pH Stability Maximum | Comment | Organism |
---|---|---|---|---|
3.4.24.61 | 4 | 9 | 3-15 h, 25% or less loss of activity | Rattus norvegicus |