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Literature summary extracted from

  • Wilkes, S.H.; Bayliss, M.E.; Prescott, J.M.
    Critical ionizing groups in Aeromonas neutral protease (1988), J. Biol. Chem., 263, 1821-1825.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.25 3-Phenyl-1-propanol
-
 Vibrio proteolyticus
3.4.24.25 3-Phenylpropionyl-L-Phe pH-dependence of inhibition Vibrio proteolyticus
3.4.24.25 3-Phenylpropionyl-Phe-NH2
-
 Vibrio proteolyticus
3.4.24.25 Acetohydroxamate
-
 Vibrio proteolyticus
3.4.24.25 Aminoacyl hydroxamates
-
 Vibrio proteolyticus
3.4.24.25 Chloroacetyl-N-hydroxy-L-Phe-L-Ala-L-Ala
-
 Vibrio proteolyticus
3.4.24.25 Glycine hydroxamate
-
 Vibrio proteolyticus
3.4.24.25 L-Leucine hydroxamate
-
 Vibrio proteolyticus
3.4.24.25 L-phenylalanine
-
 Vibrio proteolyticus
3.4.24.25 L-phenylalanine hydroxamate
-
 Vibrio proteolyticus
3.4.24.25 N-tert-Butoxycarbonyl-L-Phe hydroxamate
-
 Vibrio proteolyticus
3.4.24.25 Peptides containing a phenylalanyl residue
-
 Vibrio proteolyticus
3.4.24.25 Phe-Ala
-
 Vibrio proteolyticus
3.4.24.25 Phe-Ala-Gly
-
 Vibrio proteolyticus
3.4.24.25 Phe-Ala-Gly-Gly
-
 Vibrio proteolyticus
3.4.24.25 Phosphoryl-L-Phe-Gly-Gly
-
 Vibrio proteolyticus
3.4.24.25 Phosphoryl-Phe-Gly-Gly
-
 Vibrio proteolyticus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.24.25 0.2
-
 benzyloxycarbonyl-Gly-Phe-Gly-NH2
-
 Vibrio proteolyticus
3.4.24.25 0.32
-
 furylacryloyl-Gly-Phe-NH2
-
 Vibrio proteolyticus

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.25 Vibrio proteolyticus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.25 benzyloxycarbonyl-Gly-Phe-Gly-NH2 + H2O
-
 Vibrio proteolyticus ?
-
 ?
3.4.24.25 Benzyloxycarbonyl-Gly-Phe-NH2 + H2O
-
 Vibrio proteolyticus ?
-
 ?
3.4.24.25 Furylacryloyl-Gly-Phe-Gly-NH2 + H2O
-
 Vibrio proteolyticus ?
-
 ?
3.4.24.25 furylacryloyl-Gly-Phe-NH2 + H2O
-
 Vibrio proteolyticus ?
-
 ?
3.4.24.25 additional information overview: specificity towards extended substrates Vibrio proteolyticus ?
-
 ?

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
3.4.24.25 1150
-
 benzyloxycarbonyl-Gly-Phe-Gly-NH2
-
 Vibrio proteolyticus