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Literature summary extracted from
- Purification and characterization of a bone metalloproteinase that degrades gelatin and types IV and V collagen (1985), Biochim. Biophys. Acta, 831, 49-58.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.24.24 | additional information | rapid activation of the zymogen by 4-aminophenylmercuric acetate | Oryctolagus cuniculus | |
| 3.4.24.24 | additional information | trypsin is a poor activator | Oryctolagus cuniculus |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.24.24 | Tissue inhibitor of metalloproteinases | - |
Oryctolagus cuniculus |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.4.24.24 | extracellular | - |
Oryctolagus cuniculus | - |
- |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.4.24.24 | 61000 | - |
x * 61000, rabbit, active form, SDS-PAGE under nonreducing conditions | Oryctolagus cuniculus |
| 3.4.24.24 | 65000 | - |
x * 65000, rabbit, latent form, SDS-PAGE under nonreducing conditions | Oryctolagus cuniculus |
| 3.4.24.24 | 65000 | - |
x * 65000, rabbit, active form, SDS-PAGE under reducing conditions | Oryctolagus cuniculus |
| 3.4.24.24 | 72000 | - |
x * 72000, rabbit, latent form, SDS-PAGE under reducing conditions | Oryctolagus cuniculus |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.24.24 | Oryctolagus cuniculus | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.4.24.24 | - |
Oryctolagus cuniculus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.24.24 | culture medium | from calvariae | Oryctolagus cuniculus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.4.24.24 | additional information | - |
- |
Oryctolagus cuniculus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.24.24 | Collagen + H2O | type IV | Oryctolagus cuniculus | ? | - |
? |  |
| 3.4.24.24 | Collagen + H2O | type V | Oryctolagus cuniculus | ? | - |
? | |
| 3.4.24.24 | Elastin + H2O | - |
Oryctolagus cuniculus | ? | - |
? | |
| 3.4.24.24 | Gelatin + H2O | - |
Oryctolagus cuniculus | ? | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.4.24.24 | ? | x * 65000, rabbit, latent form, SDS-PAGE under nonreducing conditions | Oryctolagus cuniculus |
| 3.4.24.24 | ? | x * 61000, rabbit, active form, SDS-PAGE under nonreducing conditions | Oryctolagus cuniculus |
| 3.4.24.24 | ? | x * 72000, rabbit, latent form, SDS-PAGE under reducing conditions | Oryctolagus cuniculus |
| 3.4.24.24 | ? | x * 65000, rabbit, active form, SDS-PAGE under reducing conditions | Oryctolagus cuniculus |
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