EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.21.73 | plasminogen activator inhibitor 1 | phosphorylated enzyme is inhibited 50% at a concentration 4fold higher than nonphosphorylated enzyme | Homo sapiens |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.4.21.73 | 0.00092 | - |
plasminogen | phosphorylated enzyme | Homo sapiens | |
3.4.21.73 | 0.001 | - |
plasminogen | nonphosphorylated enzyme | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.21.73 | Homo sapiens | - |
nonphosphorylated and phosphorylated on serine | - |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.4.21.73 | A-431 cell | A431 epidermoid carcinoma cells | Homo sapiens | - |
3.4.21.73 | Detroit 562 cell | - |
Homo sapiens | - |
3.4.21.73 | ECV304 cell | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.21.73 | plasminogen + H2O | - |
Homo sapiens | plasmin + ? | - |
? |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.4.21.73 | 12.4 | - |
plasminogen | nonphosphorylated enzyme | Homo sapiens | |
3.4.21.73 | 14.1 | - |
plasminogen | phosphorylated enzyme | Homo sapiens |