EC Number | Cloned (Comment) | Organism |
---|---|---|
3.4.21.73 | - |
Homo sapiens |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.21.73 | plasminogen activator inhibitor 1 | binding of single-chain uPA moiety to the inhibitor occurs with lower affinity compared to binding of the two-chain uPA moiety | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.21.73 | Homo sapiens | - |
recombinant 54000 MW scuPA, plasmin-resistant rscuPA with Lys158 mutagenized to Glu and a 32000 MW form of rscuPA consisting of Leu144-Leu411 are obtained by expression of cDNA in Chinese hamster ovary cells | - |
3.4.21.73 | Mammalia | - |
recombinant 54000 MW scuPA, plasmin-resistant rscuPA with Lys158 mutagenized to Glu and a 32000 MW form of rscuPA consisting of Leu144-Leu411 are obtained by expression of cDNA in Chinese hamster ovary cells | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.21.73 | additional information | binding of single-chain uPA moiety to its substrate plasminogen occurs with lower affinity compared to binding of the two-chain uPA moiety | Homo sapiens | ? | - |
? | |
3.4.21.73 | additional information | the enzyme cleaves its cellular receptor between domains 1 and 2 | Homo sapiens | ? | - |
? | |
3.4.21.73 | plasminogen + H2O | - |
Homo sapiens | plasmin + ? | - |
? |