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Literature summary extracted from
- The enzymatic isomerization of beta-methylvinylacetyl coenzyme A and the specificity of a bacterial coenzyme A carboxylase (1960), J. Biol. Chem., 235, 3087-3092.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.3.3.3 | beta-methylcrotonyl-CoA | - |
Bos taurus |  |
| 5.3.3.3 | additional information | not inhibited by iodoacetate | Bos taurus | |
| 5.3.3.3 | N-ethylmaleimide | - |
Bos taurus | |
| 5.3.3.3 | p-chloromercuribenzoate | - |
Bos taurus | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 5.3.3.3 | 0.05 | - |
vinylacetyl-CoA | beta-methylvinylacetyl-CoA | Bos taurus | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.3.3.3 | additional information | not influenced by Na+ or K+ | Bos taurus |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.3.3.3 | Bos taurus | - |
- |
- |
| 5.3.3.3 | Gallus gallus | - |
- |
- |
| 5.3.3.3 | Pseudomonas sp. | - |
- |
- |
| 5.3.3.3 | Sus scrofa | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 5.3.3.3 | - |
Bos taurus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 5.3.3.3 | heart | - |
Sus scrofa | - |
| 5.3.3.3 | kidney | - |
Sus scrofa | - |
| 5.3.3.3 | liver | - |
Gallus gallus | - |
| 5.3.3.3 | liver | - |
Bos taurus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 5.3.3.3 | 32 | - |
substrate beta-vinylacetyl-CoA | Bos taurus |
Storage Stability
| EC Number | Storage Stability | Organism |
|---|---|---|
| 5.3.3.3 | frozen or at 5°C, stable for months | Bos taurus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.3.3.3 | 3-Hexenoyl-CoA | - |
Bos taurus | ? | - |
? | |
| 5.3.3.3 | Beta-Methylvinylacetyl-CoA | ir | Bos taurus | Beta-Methylvinylacetyl-CoA | - |
? | |
| 5.3.3.3 | additional information | not 4-pentenoyl-CoA, beta-methylvinylacetate, beta-vinylacetyl ethyl ester, 5-androstan-3,17-dione, 5-cholestenone, 5-pregnene-3,20-dione | Bos taurus | ? | - |
? | |
| 5.3.3.3 | Vinylacetyl pantetheine | - |
Bos taurus | ? | - |
? | |
| 5.3.3.3 | vinylacetyl-CoA | - |
Bos taurus | (E)-but-2-enoyl-CoA | - |
r | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 5.3.3.3 | 8 | 9 | - |
Bos taurus |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.3.3.3 | additional information | no cofactor | Bos taurus |
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Release 2023.1 (January 2023)
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