Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Muramatu, M.; Itoh, T.; Takei, M.; Endo, K.
    Tryptase in rat mast cells: properties and inhibition by various inhibitors in comparison with chymase (1988), Biol. Chem. Hoppe-Seyler, 369, 617-625.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.21.59 4-Amidinophenylpyruvic acid
-
 Rattus norvegicus
3.4.21.59 4-nitrophenyl 4-guanidinobenzoate
-
 Rattus norvegicus
3.4.21.59 benzamidine
-
 Rattus norvegicus
3.4.21.59 diisopropyl fluorophosphate
-
 Rattus norvegicus
3.4.21.59 leupeptin
-
 Rattus norvegicus
3.4.21.59 N-tosyl-L-Lys chloromethyl ketone
-
 Rattus norvegicus
3.4.21.59 trans-4-(Guanidinomethyl)cyclohexanecarboxylic acid esters most effective: trans-4-(guanidinomethyl)cyclohexanecarboxylic acid butylphenyl ester Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.21.59 120000
-
 rat, gel filtration Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.59 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.21.59
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.59 mast cell peritoneal Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.59 N-tert-Butyloxycarbonyl-Phe-Ser-Arg 4-methylcoumarin 7-amide + H2O
-
 Rattus norvegicus N-tert-Butyloxycarbonyl-Phe-Ser-Arg + 7-amino-4-methylcoumarin
-
 ?
3.4.21.59 N-tert-Butyloxycarbonyl-Val-Pro-Arg 4-methylcoumarin 7-amide + H2O
-
 Rattus norvegicus N-tert-Butyloxycarbonyl-Val-Pro-Arg + 7-amino-4-methylcoumarin
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.21.59 7.1
-
-
 Rattus norvegicus