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Literature summary extracted from

  • Von dem Borne, P.A.K.; Bajzar, L.; Meijers, J.C.M.; Nesheim, M.E.; Bouma, B.N.
    Thrombin-mediated activation of factor XI results in a thrombin-activable fibrinolysis inhibitor-dependent inhibition of fibrinolysis (1997), J. Clin. Invest., 99, 2323-2327.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.4.17.20 thrombin activation Homo sapiens
3.4.17.20 Thrombomodulin
-
 Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.17.20 2-Guanidinoethylmercaptosuccinic acid i.e. GEMSA Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.17.20 Fibrin, partially degraded + H2O Homo sapiens
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.17.20 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.17.20 plasma
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.17.20 Fibrin, partially degraded + H2O
-
 Homo sapiens Fibrin, partially degraded + L-Lys + L-Arg
-
 ?
3.4.17.20 Fibrin, partially degraded + H2O
-
 Homo sapiens ?
-
 ?