BRENDA - Enzyme Database

Dolichol (C55) mono-and pyrophosphatases of the rat liver

Applekvist, E.L.; Chojnacki, T.; Dallner, G.; Biosci. Rep. 1, 619-626 (1981)
No PubMed abstract available

Data extracted from this reference:

Activating Compound
EC Number
Activating Compound
Commentary
Organism
Structure
3.6.1.43
EDTA
-
Rattus norvegicus
Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
3.6.1.43
bacitracin
complete inhibition; no inhibition when preincubating with EDTA
Rattus norvegicus
3.6.1.43
NaF
slight inhibition
Rattus norvegicus
3.6.1.43
Triton X-100
above 0.2%
Rattus norvegicus
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
3.6.1.43
lysosome
-
Rattus norvegicus
5764
-
3.6.1.43
membrane
-
Rattus norvegicus
16020
-
3.6.1.43
microsome
-
Rattus norvegicus
-
-
3.6.1.43
mitochondrial outer membrane
plasma, outer mitochondrial membranes
Rattus norvegicus
5741
-
3.6.1.43
additional information
absent in peroxisomes and inner mitochondrial membranes
Rattus norvegicus
-
-
3.6.1.43
plasma membrane
-
Rattus norvegicus
5886
-
Metals/Ions
EC Number
Metals/Ions
Commentary
Organism
Structure
3.6.1.43
additional information
no metal ions required
Rattus norvegicus
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3.6.1.43
dolichyl diphosphate + H2O
Rattus norvegicus
involved in biosynthesis of glycoproteins, regeneration of dolichyl phosphate
dolichyl phosphate + phosphate
-
Rattus norvegicus
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
3.6.1.43
Rattus norvegicus
-
-
-
Purification (Commentary)
EC Number
Commentary
Organism
3.6.1.43
-
Rattus norvegicus
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
3.6.1.43
liver
-
Rattus norvegicus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.6.1.43
dolichyl diphosphate + H2O
-
289076
Rattus norvegicus
dolichyl phosphate + phosphate
-
289076
Rattus norvegicus
?
3.6.1.43
dolichyl diphosphate + H2O
involved in biosynthesis of glycoproteins, regeneration of dolichyl phosphate
289076
Rattus norvegicus
dolichyl phosphate + phosphate
-
289076
Rattus norvegicus
?
pH Optimum
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
3.6.1.43
8
-
-
Rattus norvegicus
Activating Compound (protein specific)
EC Number
Activating Compound
Commentary
Organism
Structure
3.6.1.43
EDTA
-
Rattus norvegicus
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
3.6.1.43
bacitracin
complete inhibition; no inhibition when preincubating with EDTA
Rattus norvegicus
3.6.1.43
NaF
slight inhibition
Rattus norvegicus
3.6.1.43
Triton X-100
above 0.2%
Rattus norvegicus
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
3.6.1.43
lysosome
-
Rattus norvegicus
5764
-
3.6.1.43
membrane
-
Rattus norvegicus
16020
-
3.6.1.43
microsome
-
Rattus norvegicus
-
-
3.6.1.43
mitochondrial outer membrane
plasma, outer mitochondrial membranes
Rattus norvegicus
5741
-
3.6.1.43
additional information
absent in peroxisomes and inner mitochondrial membranes
Rattus norvegicus
-
-
3.6.1.43
plasma membrane
-
Rattus norvegicus
5886
-
Metals/Ions (protein specific)
EC Number
Metals/Ions
Commentary
Organism
Structure
3.6.1.43
additional information
no metal ions required
Rattus norvegicus
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3.6.1.43
dolichyl diphosphate + H2O
Rattus norvegicus
involved in biosynthesis of glycoproteins, regeneration of dolichyl phosphate
dolichyl phosphate + phosphate
-
Rattus norvegicus
?
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
3.6.1.43
-
Rattus norvegicus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
3.6.1.43
liver
-
Rattus norvegicus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.6.1.43
dolichyl diphosphate + H2O
-
289076
Rattus norvegicus
dolichyl phosphate + phosphate
-
289076
Rattus norvegicus
?
3.6.1.43
dolichyl diphosphate + H2O
involved in biosynthesis of glycoproteins, regeneration of dolichyl phosphate
289076
Rattus norvegicus
dolichyl phosphate + phosphate
-
289076
Rattus norvegicus
?
pH Optimum (protein specific)
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
3.6.1.43
8
-
-
Rattus norvegicus